Using CBD in defined doses for medicinal purposes is one thing, but putting it in food and beverages is something entirely different. Someone may wind up getting CBD from multiple products, and so their daily dose could vary significantly. Taking a standardized dose of CBD oil daily as a recognized medicinal is a very different thing from taking uncontrolled doses of CBD isolate daily infused artificially into food and beverage products, and the long term risk may be very different — no one really knows for sure.
The wide range of benefits associated with cannabis have garnered interest for use in cancer therapy. Research suggests that cannabinoids, including CBD, may have anti-tumor effects. While this is not enough to define cannabis as a treatment for cancer, it does make it attractive as a complement to other therapies, for both reducing symptoms and possibly enhancing the effects of anticancer drugs. 

Another highly flavorful oil, Sasson says that this one goes a long way. "Sesame oil adds so much to a dish, so you don't need [to use] a lot," she explains. If you have a peanut allergy (or just aren't fond of that peanut flavor), this is a great alternative to peanut oil. And like extra-virgin olive oil, it's cold-pressed rather than chemically processed. So while it may not have the highest smoke point ever (350 to 410 degrees F), it's a good unrefined option, if that's what you're looking for.
Vegetable oil is kind of a sister to canola oil. It's also chemically processed, has a similarly high smoke point (400 to 450 degrees F), and is neutral flavor. Again, these characteristics make it good for roasting, frying, and baking. And like vegetable oil, Sasson and Shaw say it’s not the healthiest oil ever since the chemical processing depletes the natural mineral content—and that's why it has that high smoke point.

Full Spectrum CBD Oil is commonly used for assisting with pain, stress, sleep, anxiety, and more. To assist with Pain, Stress, Anxiety take as recommended once a day in the morning. To assist with sleep take as recommended in the evening. All of Zatural's Hemp products are always 0 THC. If needed, one may increase the daily recommended dosage slowly according to their needs. 

Some makers of grapeseed oil will go on about how “pure” and wholesome their product is compared to other oils, or even other brands of grapeseed oil. That’s probably because most grapseed oil is industrially processed with hexane and other toxic, carcinogenic solvents used to extract and clean the oil, with traces of these chemicals remaining in the final product. However, an expeller-pressed processed grapeseed oil is still rife with polyunsaturated fat, in concentrations which are highly toxic to humans. Doesn’t matter how “pure” those PUFAs are.”
Hemp oil is also rich in "super" polyunsaturated fatty acids, most notably gamma-linolenic acid and stearidonic acid. Although these are not essential fatty acids, they may help reduce the symptoms of atopic dermatitis and other skin conditions. However, the amount of these non-essential fatty acids varies according to the quality of the hemp plant the acids were derived from.
^ Jump up to: a b c d Campos AC, Moreira FA, Gomes FV, Del Bel EA, Guimarães FS (December 2012). "Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences (Review). 367 (1607): 3364–78. doi:10.1098/rstb.2011.0389. PMC 3481531. PMID 23108553.
There are several techniques for extracting CBD oil from the cannabis plant. The extraction method determines whether the active CBD compound gets processed as a “full spectrum oil” or an “isolate.” A CBD isolate is a pure compound with no other active compounds or cannabinoids at all. A full spectrum oil contains other active plant compounds in addition to the CBD such as CBN (cannabinol) and cannabis terpenes (the part of the plant that gives the plant its aroma), and more. 
Avocado oil. Avocado oil is high in monounsaturated fatty acids and can promote healthy cholesterol levels and enhance absorption of some nutrients, according to a review of avocado benefits published in the May 2013 Critical Reviews in Food Science and Nutrition. Avocado oil also has a high smoke point and is therefore one of the best oils for high-temperature cooking. It can be used for stir-frying, sautéing, or searing, Haas says.
While very few clinical trials have explored the pain-relieving effects of CBD oil, a report published in the Cochrane Database of Systematic Reviews in 2018 examined the use of a variety of cannabis-based medicines and found they might be of some benefit in the treatment of chronic neuropathic pain. A type of pain triggered by damage to the somatosensory system (i.e., the system responsible for processing sensory stimuli), neuropathic pain often occurs in people with conditions like diabetes and multiple sclerosis.

I Love this Product! I've spent thousands of dollars over the last thirty years on vitamins and natural products to help me with my ADHD. This is better than anything I've tried before. It's also a lot cheaper. I don't lose my temper like I used to. It has improved my marriage. It has calmed my gut. I am much more productive both at home and at work. I feel like a normal calm human being again! I haven't found any bad side effects. I am recommending it to family and friends. Thank You!

Since the 1960’s, medical research has collected research supporting the safety of CBD. Typical doses of 10mg to 100mg a day show no negative effects. Even one study where patients took 1,280 mg a day did not see a problem. The director of the National Institute of Drug Abuse has stated that CBD oil is safe, and recently the FDA approved CBD oil for use in children with epilepsy. 
I just started taking CBD oil , I am on my 2nd Hip replacement surgery due to device failures looking at a 3rd surgery. Has you can imagine the pain, stress and anxiety levels are off the charts. Especially at an otherwise healthy 54 yr women. So i understand from reading posts its best to take it under the tongue. I am taking 1-2 ml a day. I can tell some difference,is your recommended dosage. I am using for pain , stress and sleep. I appreciate your feedback.
The list includes marijuana (undifferentiated by strain) and heroin. (While the federal government oversees marijuana research, marijuana use is regulated, in part, by state laws.) As a result, scientists who study the compound must follow a host of restrictive rules. Last year, responding to a request from several governors to change marijuana’s designation, the Drug Enforcement Administration announced that all cannabis would remain a Schedule 1 drug.
Stephanie, generally, I have patients take 20 to 150mg a day for sleep +/- anxiety. Start low and go slow. Know the dosages of your product. Usually 2/3 to 3/4 of the daily dose is 1-2 hours before bedtime, and the other portion is upon waking (to improve wakefulness during the day). Other factors such as stress, hormone replacement, other meds & medical conditions, etc. play a role along with individual differences. I own a compounding pharmacy, so we see a lot of unique needs. I can't give more specific advice in this forum, but there is help!

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Vegetable oil is kind of a sister to canola oil. It's also chemically processed, has a similarly high smoke point (400 to 450 degrees F), and is neutral flavor. Again, these characteristics make it good for roasting, frying, and baking. And like vegetable oil, Sasson and Shaw say it’s not the healthiest oil ever since the chemical processing depletes the natural mineral content—and that's why it has that high smoke point.
This is true despite the fact that unlike marijuana, hemp contains only trace levels of THC (tetrahydrocannabinol), the chemical component that gives marijuana its euphoric qualities. Instead, hemp is primarily known for its fibers, commonly used to make rope, fabrics, auto parts, industrial materials, and a variety of other products. Hemp is also known for its highly-nutritious seeds (a.k.a. hemp hearts), which have been shown to benefit heart health, skin diseases, and more.

Lisa Sasson, clinical associate professor of nutrition at NYU Steinhardt, is obsessed with extra-virgin olive oil, and who can blame her. It's high in heart-healthy monounsaturated fats and a quality bottle can truly take you on a taste bud adventure. There's one catch with extra-virgin versus other grades of olive oil: It has a relatively low smoke point (325 to 375 degrees F), which means you may not want to use it for frying or roasting at temperatures above that smoke point. Additionally, cooking a good EVOO will break down its structural integrity which messes with both its flavor and nutrition, so you may want to save your fancy bottle for drizzling and finishing dishes. Find out just how to find your perfect bottle here.
There's also the question of CBD's legality – something that's a lot grayer than the black-and-white picture most companies paint. The U.S. Drug Enforcement Administration considers CBD, like all cannabinoids, a schedule 1 drug. That means it's just as illegal as heroin and ecstasy. Meanwhile, hemp – a variety of the cannabis plant regulated by the U.S. Department of Agriculture – is legal , so long as its THC content is negligibly low. But because the agriculture department doesn't test for CBD – only THC – in hemp, more companies are getting away with selling products they say contain CBD, says Sara Jane Ward, an assistant professor of pharmacology at the Temple University Lewis Katz School of Medicine who's been studying CBD in rodent models for more than 10 years. Needless to say, the legality of CBD is "very confusing and very gray," she says.
Though clinical and anecdotal evidence suggests CBD’s benefits in managing different conditions, it became most famous for treating a rare and debilitating form of pediatric epilepsy. Dravet’s Syndrome is notoriously resistant to current approved treatment methods. Sufferers are plagued by seizures, often up to hundreds a day, that worsen as they age and can be life-threatening. Currently, treatment methods include having the child wear an eyepatch, specialized diets, and brain surgery, but all have mixed success rates.

Tammy et al, Through trial and error you will find a correct dosage. Try 50 mg daily....25 each 2x daily....if no results up the dosage until it works for you. Remember, there has never been a death from marijuana or CBD use. You might want to try a tincture or rub with CBD and THC. You won't get the psych high from it. Helps my friend with PArkinsons tremors. She takes 50mg of tincture and uses the rub morning and night. It is a miracle for arthritis. Good luck


CBD concentrates typically contain the strongest dosage of CBD compared to any other CBD products. It can contain up to 10 times the average CBD products. Concentrates are also convenient in that it only takes a few seconds to consume. Overall, CBD concentrates seem to be most popular among customers who are extremely busy, yet seek high potency CBD.
I have been taking cbd capsules for some time and they have helped my mood greatly. However, I did not get any pain relief from them. I was paying $86.00 a month for 30 pills and it was a hardship but I felt it was worth it. I saw your pills on Amazon and thought for 5mg more than what I was taking it was worth a try. I fell awhile back and was in pain most of the time and within 1hr after taking the pill the pain diminished. I was amazed. I am blessed that I found these pills and would heartily recommend them to anyone with either affliction.
Of course, because legal marijuana is in such a confusing transitional period, even here there are potential exceptions. The U.S. Food and Drug Administration (FDA) approved Epidiolex, a treatment for a rare form of pediatric epilepsy that contains CBD. The DEA decided to classify this as a Schedule 5 drug, the scheduling that indicates the lowest potential for addiction and abuse.
The main points are to use cooking oils in moderation, Lichtenstein said. The government's U.S. Dietary Guidelines recommend that Americans include a small amount of oils in their diets every day to supply essential fatty acids, because the body can't make these acids and thus must get them from food. There are two such fatty acids, and both are polyunsaturated fatty acids: linoleic acid and alpha-linolenic acid.

The CBD oil we offer has a couple different applications. You can hold a sublingual dose under the tongue for 30-60 seconds (recommended for fastest absorption), apply the oil topically to your skin (can be applied directly to a problem area or mixed with your favorite moisturizer), or blend the oil in a health-conscious smoothie. We will include further dosing instructions with the product.


After seasonal harvests of specific cultivars, these high-CBD hemp crops are put through a specialized solvent-free extraction process to yield a hemp oil that is naturally high in cannabidiol. This pure hemp extract is then tested for safety, quality, and cannabinoid content before being exported to our processing facilities in the United States. Importing any cannabis or hemp product into the United States is a complicated and serious task, so we leave nothing to chance before our high-CBD hemp oil makes its journey across the Atlantic Ocean.
There are thousands of unique varieties of hemp. The cultivars used for CBD oil contain significantly higher concentrations of CBD than others. Using these uniquely potent plants, it is possible to extract cannabis oil that contains significant levels of cannabidiol, as well as essential vitamins, minerals, fatty acids, terpenes, flavonoids, and other non-psychoactive cannabinoids.
But, uh, what is it that CBD is supposed to do? I visited a cannabis dispensary in Boulder to find out what the hype was all about. After passing an ID check, I was introduced to a “budtender” who pointed me to an impressive array of CBD products — tinctures, skin patches, drink powders, candies, salves, massage oil, lotions, “sexy time personal intimacy oil” and even vaginal suppositories to treat menstrual cramps.
I purchased this product locally and as I walked back to my car, I was in so much pain in my feet and hands I wasnt sure I could make it back. I sat in my car and took a dropper full (1ml). As I was sitting there I could feel the inflammation in my hands disappear and the pain went away. My feet began to feel the effects next and the pain all but subsided. I hadnt been sleeping very good at night but last night I slept like a baby with NO pain. Why isnt this marketed as a product that is NON opiod and covered by insurance? Rheumatoid Arthritis is the most painful thing in the world but this helped me 100%. I almost cried last night I was so happy for a change! Thank you for making this product.
The CBD oil we offer has a couple different applications. You can hold a sublingual dose under the tongue for 30-60 seconds (recommended for fastest absorption), apply the oil topically to your skin (can be applied directly to a problem area or mixed with your favorite moisturizer), or blend the oil in a health-conscious smoothie. We will include further dosing instructions with the product.
Most of us regard cooking oil as nothing more than a means to a non-sticking end. But (and this is a big, prepare-to-gag kind of but) the average American consumes a whopping 36 pounds of cooking oils per year — more than three times as much as in the early 1970s. These oils contributed more than 400 calories to our daily diet in 2010 (the Census Bureau suspiciously quit collecting data on how much fat and oil companies produce in 2011, meaning the Department of Agriculture can no longer use that data to accurately calculate how many calories cooking oil contributes to the average American diet).
The omega 3 and omega 6 fatty acids found in hemp oil are classified as polyunsaturated meaning that they are a healthy dietary fat. These compounds are extremely beneficial to the body and are ideal for human nutrition, except when taken in excess. Overindulgence of polyunsaturated fatty acids has previously been linked to cardiac dysfunction, cancer growth, and an increased susceptibility to bacterial infections.
My dad has severe advanced stage Dementia. Will CBD oil help him at this point? He is now refusing to eat any solid food, but will accept most drinks.In addition, he has lost a great deal of weight even though they're giving him Mega Shakes containing a full meals worth of proteins, etc. He gets at least 4 of these a day..some which he refuses. Is his Dementia too far gone for CBD oils to help him?
I have crohns dibeates 2 stage kidney failure I take 6000 mg of chemicals a day when I get a flair l might lose a lot of blood I've had fistula surgery once darn mean killed me 2 more just gut surgerys little bit of gut removed I tease my gut doctor he schoold just put in a zipper any way I'm looking for something natural to try for pain also where I live if you get caught automatic life so the delima begins how much would any one suggest starting out with thanks for your time also compared to most of the folks mine seems like a minor problem on this site but I would appreciate some advice I hope all you folks have good lives and remember god always loves you even though sometimes you think he may have forgotten you
Final thoughts: Hemp oil and hemp derived CBD oil is legal in all fifty states, but there certainly is a stigma to it. Because of that it can be very hard to find reliable information to educate yourself with. This is a great dietary supplement and may help decrease inflammation, improve skin, help with mild pain, etc. If you have severe pain, hemp derived CBD oil may be what you need.

CBD concentrates typically contain the strongest dosage of CBD compared to any other CBD products. It can contain up to 10 times the average CBD products. Concentrates are also convenient in that it only takes a few seconds to consume. Overall, CBD concentrates seem to be most popular among customers who are extremely busy, yet seek high potency CBD.


Green Roads CBD oil products are both easy to use and offer all of the benefits associated with CBD and hemp. CBD oil can be used sublingually via a dropper, or it can be added to your food and beverages which is why most new users have made it their go-to CBD product of choice. Every item in our collection of CBD oils has been formulated by our licensed pharmacist of 25 plus years and then tested by independent labs to ensure that we comply with all industry standards and regulations.
In 2015, The Hebrew University of Israel published a study that documented the potency of single-molecule CBD extract versus the potency of whole-plant CBD-rich extract. It found that extract taken from whole plant CBD-rich cannabis is therapeutically superior to single-molecule extract. The scientists behind this study noticed that science had been utilizing pure, single-molecule CBD, which resulted in a bell-shaped dose-response curve. This means that CBD’s efficacy plummets at very high and very low doses.

I am a senior citizen with problem with my lower back, shoulder and neck pain, scar tissue discomfort from breast cancer surgeries, right ankle pain, doctor's diagnosed me with osteoarthritis, discomfort with closing my left hand whereas I can't make a fist, wrist pain that can cause me to drop a plate from time to time, and last but not least is knee pain even though I have had knee replacement surgery. I am in pain 24/7 and have tired to just endure without constantly taking OTC medications. I refuse to continue taking prescription medications. As I was researching about Black Seed Oil then I came up on HEMP Seed Oil. There are many strengths but I decided on the 350 mg. I read about the benefits of Hemp Seed and decided to give it a try. But before I could, I had to find the right one. There are so many hemp seed oils out there and not all are as good as the one that I selected according to reading the reviews of others. My Beyond Bliss Hemp Seed Oil was delivered very quickly and I tried it the very same day. To my amazement, the pain in my knee, hand, wrist, chest went away that very night. I woke up feeling more refreshed with a good night sleep. I still have a little discomfort with my neck and shoulders but I'm hoping that with dissipate with more intake of the Beyond Bliss Hemp Seed Oil. For most of my pain to go away within the first try; this is a miracle for me and a keeper. I've already ordered and paid for another bottle for my daughter. The company sent a 'thank you for your order card and instructions to request a free bottle'. I am so impressed that I had to order another bottle for my daughter that has problems with her knee and foot when she walks, I just could not wait for the free bottle and that's why I decided to order one for her. Again, this is a good product that should hopefully work for you. All I can say is to give this company a try, I don't feel you will go wrong.
Speaking of which: The difference between olive oil and extra virgin olive oil, if you were wondering, is essentially that extra virgin olive oil is less processed, meaning it’s both slightly healthier and more flavorful. As such, extra virgin olive oil is best in dressings, spreads and marinades, while regular olive oil works better for general cooking and sautéing. 

I have sporadic back spasms for year I see a chiropractor monthly for maintenance (it help) and deal with daily Knee & hip joint pain due to my job (heavy mechanic/steel work with lots of walking). after reading all the great reviews on CBD oil I want to get off the daily ibuprofen regiment and try CBD oil. I would like to try it as a gel cap but would like some advise on dosage size. I also want to know how often I should take the CBD treatments. any and all advise is appreciated

Hi, I have had spondylolisthesis since age 11 which left me with extreme nerve pain...restless leg syndrome. Had 3 spinal ops and also had hip surgery 2 years ago. have asthma and hypothyroidism. I can deal with everything else but this nerve pain is insane. Used Gabapentin for 9 years and now its not in the market in Nairobi, Kenya where I live. Am on Lyrica, which is not working. I started Cbd oil in August but now found my body has become immune to the effects of pain releif I was getting. Can anyone suggest what strength oil/cbd supplement I should aim for? Currently am making flapjacks with weed, have one every night but this makes me high which I dont want. I still wake up in pain at night, please help.

I started using hemp oil a week ago…i baked some bite sized pasties today for daily dosea…i put 2 cap fills in my bath also. EVERYTHING HAS CHANGED… my depression is lifting my appetite has lessened I don’t want to sleep all day my sight clearer, skin smoother and face looks less aged. My pain has subsided substantially…i feel like a new person. I am in aww of this amazing life changing product I bought a 32 oz bottle and I use it for everything. Oh ya and my digestion is in way better condition…

Phytocannabinoid-rich hemp oil has a higher concentration of CBD compared to other cannabinoids. When ingested, CBD interacts with our body’s endocannabinoid system. This triggers the body to consume more of its own cannabinoids, which directly influences our immune system—where the majority of CBD receptors are found. This helps reduce inflammation and pain and promotes a healthier immune system.


CBD concentrates typically contain the strongest dosage of CBD compared to any other CBD products. It can contain up to 10 times the average CBD products. Concentrates are also convenient in that it only takes a few seconds to consume. Overall, CBD concentrates seem to be most popular among customers who are extremely busy, yet seek high potency CBD.
THC is the primary psychoactive compound in marijuana and it is what people are searching for when they want a product that gives them a "high." Unlike THC, CBD isn't known to cause psychoactive effects, and is therefore attractive to those who want to avoid the high but who believe there are other benefits of CBD, said Sara Ward, a pharmacologist at Temple University in Philadelphia. [Healing Herb? Marijuana Could Treat These 5 Conditions]
CBD products that don't contain THC fall outside the scope of the U.S. Drug Enforcement Agency's (DEA) Controlled Substances Act, which means CBD products are legal to sell and consume as long as they don't have THC. That's likely one of the reasons why CBD products, including CBD oil, are becoming more socially acceptable and increasingly popular. In 2016, Forbes reported that CBD products are expected to be a $2.2 billion industry by 2020.
Disclaimer: This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A Doctor's advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are property of their respective owners and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Individual weight loss results will vary. By using this site, you agree to follow the Privacy Policy and all Terms & Conditions printed on this site. Void Where Prohibited by Law.
Grown and extracted from the USA, our quality CBD is fully compliant under the Kentucky Department of Agricultural Industrial Hemp Pilot Program. Our CBD products are legal and shipped to all 50 states and internationally. All of our CBD products contain 0% THC, guaranteed. We utilize a whole plant CO2 extraction that allows us to draw the CBD from the plant material and filter out unnatural substances, maximizing pure CBD concentration. Each and every product that leaves the facility is third-party tested to ensure consistency and quality.

Cannabidiol can be taken into the body in multiple ways, including by inhalation of cannabis smoke or vapor, as an aerosol spray into the cheek, and by mouth. It may be supplied as CBD oil containing only CBD as the active ingredient (no added tetrahydrocannabinol [THC] or terpenes), a full-plant CBD-dominant hemp extract oil, capsules, dried cannabis, or as a prescription liquid solution.[2] CBD does not have the same psychoactivity as THC,[9][10][11] and may affect the actions of THC.[7][8][9][12] Although in vitro studies indicate CBD may interact with different biological targets, including cannabinoid receptors and other neurotransmitter receptors,[9][13]as of 2018 the mechanism of action for its biological effects has not been determined.[8][9]

"It's important to know that the research in this area is in its infancy, partly because we haven't really understood much about CBD until relatively recently," said Marcel Bonn-Miller, an adjunct assistant professor at the University of Pennsylvania Perelman School of Medicine. He pointed out that the classification of marijuana as a Schedule 1 drug by the DEA makes it difficult to get material to use in laboratory studies. Schedule 1 drugs have a high potential for abuse, according to the DEA, and are illegal under federal law.
Jackson Leyden had always been a healthy kid; he practiced taekwondo, and he played lacrosse and baseball. But in 2011, a few months after his eighth birthday, he began having seizures several times a day. Many were brief, a half-minute of staring into space, but he also had severe episodes in which he would collapse, sometimes injuring himself. Over the next two years, he was hospitalized about 50 times, and he missed much of fourth and fifth grade.
This is a guest post by Michael Joseph who is a passionate nutrition educator with a master’s degree in Nutrition Education. He is the founder of Nutrition Advance where he frequently writes nutrition and health-related articles. He believes that nutrition advice has become overly complicated and that we need to get back to the basics and value our traditional food. Photo credits go to Nutrition Advance.

despite what you say on canola and soybean oil being healthy i strongly disagree with you after my research on both of them. Canola oil is not really a natural oil it is manufactured oil from rapeseed. “Canola oil is made with a highly unnatural processing method that involves high heat, deodorization and the toxic solvent hexane. Significant amounts of trans fats are formed during this process.” also “One study analyzed canola and soybean oils found on store shelves in the U.S. They found that 0.56% to 4.2% of the fatty acids in them were toxic trans fats “
I started using hemp oil a week ago…i baked some bite sized pasties today for daily dosea…i put 2 cap fills in my bath also. EVERYTHING HAS CHANGED… my depression is lifting my appetite has lessened I don’t want to sleep all day my sight clearer, skin smoother and face looks less aged. My pain has subsided substantially…i feel like a new person. I am in aww of this amazing life changing product I bought a 32 oz bottle and I use it for everything. Oh ya and my digestion is in way better condition…
This oil has a couple interesting characteristics: For one, it's high in omega-3 fatty acids, and Sasson says you may want look into using it more often if you don't eat a lot of fish. But she says you absolutely can't cook with it, because it's incredibly sensitive to heat and oxidizes quickly. For this reason, she says you'll want to buy small bottles so you can use it up quickly, and be extra sure to store it in a cool dark place. She suggests drizzling it over dips like hummus, or using it in salad dressings.

Over decades, researchers have found that THC may help treat pain, nausea, loss of appetite and other problems, while CBD was thought to be biologically inactive in humans. But in the past 10 years, scientists have concluded that CBD may be quite useful. Dozens of studies have found evidence that the compound can treat epilepsy as well as a range of other illnesses, including anxiety, schizophrenia, heart disease and cancer. 
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